Metastatic prostate cancer is a type of advanced prostate cancer where the cancer cells have spread to other parts of the body. It is the most serious form of prostate cancer, as it is incurable and can be fatal. Common sites of metastasis are the bones, lymph nodes, and lungs. Symptoms vary depending on the location of the spread and may include pain, difficulty urinating, and weight loss. Treatment options include hormone therapy, chemotherapy, radiation, and surgery. Early detection and treatment are key to managing metastatic prostate cancer.
Flat cells, or squamous cells, are more likely to become metastatic than cuboidal cells. This is due to the fact that flat cells have a greater surface area to volume ratio. This means that they have a greater ability to absorb nutrients, which allows them to proliferate and spread more quickly than cuboidal cells. Additionally, flat cells are more likely to attach to surfaces, which helps them to spread more easily. Finally, flat cells are more likely to form protrusions, which helps them to penetrate barriers and migrate more easily.