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Flat cells, or squamous cells, are more likely to become metastatic than cuboidal cells. This is due to the fact that flat cells have a greater surface area to volume ratio. This means that they have a greater ability to absorb nutrients, which allows them to proliferate and spread more quickly than cuboidal cells. Additionally, flat cells are more likely to attach to surfaces, which helps them to spread more easily. Finally, flat cells are more likely to form protrusions, which helps them to penetrate barriers and migrate more easily.
